Chemical composition, total phenolic content and antimicrobial activities of Zhumeria majdae

Document Type: Original research


Transfer Phenomena Laboratory (TPL), Department of Food Science, Technology and Engineering, Faculty of Biosystems Engineering, University of Tehran


Zhumeria majdae is a rare an endemic medicinal plantspecies grown wild in Iran. The hydro distilled essential aerial part oil of Z. majdae analysed by GC–MS. Thirty-one compounds representing 95.36% of the aerial part oil, respectively, were identified, of which linalool (48.14%), camphor (20.71%), limonene (4.83%), trans-linalool oxide (2.69%), 3-Octanone (2.34%), terpinene-4-ol (2.30%), camphene (1.88%), caryophyllene oxide (1.34%), geraniol (1.23%), α-pinene (1.22%), p-Cymene (1.08%) were the major compounds. Total phenolic content was 42.74 mg GAE/g dw and the IC50 in the radical scavenging assay was 32.08 mg/ml. The hydro distilled essential aerial part oil display potential of antibacterial activity against the tested 8 phytopathogenic bacterial such as Bacillus cereus, Bacillus thuringiensis, Enterococcus faecalis, Staphylococcus epidermidis, Salmonella typhimurium, Campylobacter jejuni, Klebsiella pneumoniae and Pseudomonas fluorescens. The inhibition zones and MIC values for all test strains, which were sensitive to the essential oil of Z. majdae were in the range of 33-30 mm and 0.93 mg/ml, respectively. The results support the traditional usage and also possible use of Z. majdae essential oil and extracts in the food, pharmaceutical and cosmetic industries.


Ahmad, J. I. (1996). Free radicals and health: is vitamin E the answer? Food Science and Technology Today (United Kingdom).
Ahn, D. U., Olson, D. G., Lee, J. I., Jo, C., Wu, C., & Chen, X. (1998). Packaging and irradiation effects on lipid oxidation and volatiles in pork patties. Journal of Food Science, 63(1), 15–19.
Akin, M., Aktumsek, A., & Nostro, A. (2010). Antibacterial activity and composition of the essential oils of Eucalyptus camaldulensis Dehn. and Myrtus communis L. growing in Northern Cyprus. African Journal of Biotechnology, 9(4).
Aligiannis, N., Kalpoutzakis, E., Mitaku, S., & Chinou, I. B. (2001). Composition and antimicrobial activity of the essential oils of two Origanum species. Journal of Agricultural and Food Chemistry, 49(9), 4168–4170.
Arman, M., Yousefzadi, M., & Ebrahimi, S. N. (2009). Antimicrobial activity and composition of the essential oil from Zhumeria majdae Rech. f. & Wendelbo. Journal of Essential Oil Bearing Plants, 12(5), 630–634.
Athie, I., & Mills, K. A. (2005). Resistance to phosphine in stored-grain insect pests in Brazil. Brazilian Journal of Food Technology, 8(1/2), 143–147.
Bachir, R. G., & Benali, M. (2012). Antibacterial activity of the essential oils from the leaves of Eucalyptus globulus against Escherichia coli and Staphylococcus aureus. Asian Pacific Journal of Tropical Biomedicine, 2(9), 739–742.
Baratta, M. T., Dorman, H. J. D., Deans, S. G., Figueiredo, A. C., Barroso, J. G., & Ruberto, G. (1998). Antimicrobial and antioxidant properties of some commercial essential oils. Flavour and Fragrance Journal, 13(4), 235–244.
Buckley, D. J., Morrissey, P. A., & Gray, J. I. (1995). Influence of dietary vitamin E on the oxidative stability and quality of pig meat. Journal of Animal Science, 73(10), 3122–3130.
Cavar, S., Maksimovic, M., Vidic, D., & Paric, A. (2012). Chemical composition and antioxidant and antimicrobial activity of essential oil of Artemisia annua L. from Bosnia. Industrial Crops and Products, 37(1), 479–485.
Chowdhury, H., Kar, C. S., Sarkar, S. K., & Tripathi, M. K. (2012). Feeding inhibitory effect of some plant extracts on jute hairy caterpillar (Spilosoma obliqua). Indian Journal of Agricultural Sciences, 82(1), 59–62.
Diao, W.-R., Hu, Q.-P., Feng, S.-S., Li, W.-Q., & Xu, J.-G. (2013). Chemical composition and antibacterial activity of the essential oil from green huajiao (Zanthoxylum schinifolium) against selected foodborne pathogens. Journal of Agricultural and Food Chemistry, 61(25), 6044–6049.
Diao, W.-R., Hu, Q.-P., Zhang, H., & Xu, J.-G. (2014). Chemical composition, antibacterial activity and mechanism of action of essential oil from seeds of fennel (Foeniculum vulgare Mill.). Food Control, 35(1), 109–116.
Didry, N. p, Dubreuil, L., & Pinkas, M. (1993). Antibacterial activity of thymol, carvacrol and cinnamaldehyde alone or in combination. Die Pharmazie, 48(4), 301–304.
Edris, A. E. (2007). Pharmaceutical and therapeutic potentials of essential oils and their individual volatile constituents: a review. Phytotherapy Research: An International Journal Devoted to Pharmacological and Toxicological Evaluation of Natural Product Derivatives, 21(4), 308–323.
Hossain, M. A., Shah, M. D., Sang, S. V., & Sakari, M. (2012). Chemical composition and antibacterial properties of the essential oils and crude extracts of Merremia borneensis. Journal of King Saud University-Science, 24(3), 243–249.
Hosseinzadeh, H., Ramezani, M., Fadishei, M., & Mahmoudi, M. (2002). Antinociceptive, anti-inflammatory and acute toxicity effects of Zhumeria majdae extracts in mice and rats. Phytomedicine, 9(2), 135–141.
Isman, M. B. (2006). Botanical insecticides, deterrents, and repellents in modern agriculture and an increasingly regulated world. Annu. Rev. Entomol., 51, 45–66.
Jones, P. J. H., & AbuMweis, S. S. (2009). Phytosterols as functional food ingredients: linkages to cardiovascular disease and cancer. Current Opinion in Clinical Nutrition & Metabolic Care, 12(2), 147–151.
Jordán, M. J., Lax, V., Rota, M. C., Lorán, S., & Sotomayor, J. A. (2013). Effect of bioclimatic area on the essential oil composition and antibacterial activity of Rosmarinus officinalis L. Food Control, 30(2), 463–468.
Juven, B. J., Kanner, J., Schved, F., & Weisslowicz, H. (1994). Factors that interact with the antibacterial action of thyme essential oil and its active constituents. Journal of Applied Bacteriology, 76(6), 626–631.
Mahboubi, M., & Feizabadi, M. M. (2009). Antimicrobial activity of essential oils from 13 different plants against streptococci. International Journal of Essential Oil Therapeutics, 3(1), 40–44.
Mahboubi, M., Bokaee, S., Dehdashti, H., & Feizabadi, M. M. (2012). Antimicrobial activity of Mentha piperitae, Zhumeria majdae, Ziziphora tenuior oils on ESBLs producing isolates of Klebsiella pneumonia. Biharean Biol, 6, 5–9.
Majrouhi, A. A. (2009). Chemical composition of the leaf essential oil of Zhumeria majdae growing in South Iran. Chemistry of Natural Compounds, 45(3), 429–430.
Mitscher, L. A., Drake, S., Gollapudi, S. R., & Okwute, S. K. (1987). The society for applied microbiology. J. Appl. Microbiol, 86, 985–990.
Mohaddese, M., & Nastaran, K. (2009). Antimicrobial activity of Zhumeria majdae Rech. F. & Wendelbo essential oil against different microorganisms from Iran. Pharmacognosy Magazine, 5(19), 105.
Morris, J. A., Khettry, A., & Seitz, E. W. (1979). Antimicrobial activity of aroma chemicals and essential oils. Journal of the American Oil Chemists’ Society, 56(5), 595–603.
Omidpanah, N., Valifard, M., Esmaeili, M., Yousefi, R., & Moghadam, A. (2015). Antioxidant and antibacterial properties of the essential oils of two Iranian Medicinal Plants: Zhumeria majdae and Salvia mirzayanii. Journal of Advanced Medical Sciences and Applied Technologies (JAMSAT), 1(1).
Prakash, A., & Rao, J. (2018). Botanical pesticides in agriculture. CRC press.
Rababah, T. M., Hettiarachchy, N. S., & Horax, R. (2004). Total phenolics and antioxidant activities of fenugreek, green tea, black tea, grape seed, ginger, rosemary, gotu kola, and ginkgo extracts, vitamin E, and tert-butylhydroquinone. Journal of Agricultural and Food Chemistry, 52(16), 5183–5186.
Shahidi, F., Janitha, P. K., & Wanasundara, P. D. (1992). Phenolic antioxidants. Critical Reviews in Food Science & Nutrition, 32(1), 67–103.
Sharififar, F., Mozaffarian, V., Moshafi, M. H., Dehghan-Nudeh, G., Parandeh-Rezvani, J., & Mahdavi, Z. (2007). Chemical composition and biological activities of Zhumeria majdae Resh. F. & Wendelbo. Jundushapur J Natur Pharm Prod, 2008(1), 8–18.
Zargari, A. (1995). Medicinal plants (Vol. 1050400844). Teheran, Iran: Tehran University Publications.